The unique action of a PURE-LIGHT TECHNOLOGIES light bulb is that it uses light in a photocatalytic action to continuously create two special types of super oxygen molecules called Superoxide (0-2) and Hydroxyl ion radical (HO) that breakdown bacteria, viruses, mold, and also breakdown toxic VOC pollutants. The air that we breathe is full of these bacteria, viruses, mold, toxic pollutants (called VOC--Volatile Organic Compounds like Carbon Monoxide, Benzine, Formaldahyde...) especially in enclosed areas like hospitals, schools, businesses, and homes looking for a place to land and grow. As air comes near a light bulb coated in our Pure-Light formula, it gets cleansed of these bacteria, viruses, mold, and pollutants. The air also gets deoderized as well. There is also a secondary PURE-LIGHT effect on the surfaces of items near the light bulb, such as kitchen/bathroom counters, dishes, stoves, cutting boards, door knobs, etc.
• The unique photocatalytic phenomenon or action was discovered in 1967.
• Superoxide (O-2) inside the body, or in the air, combines with a microorganism giving it essentially a boost of oxygen. Good cells thrive with the extra oxygen while viruses and bacteria are killed by the extra oxygen.
Superoxides are also used in firefighterers' oxygen tanks and divers rebreather systems in order to provide a readily available source of oxygen.
The HYDROXYL ION radical (HO) is often referred to as the "detergent" of the atmosphere because it reacts with many pollutants called VOCs (Volatile Organic Compounds), often acting as the first step to their removal.
Hydroxyl radicals also attack the porous cell walls of bacteria and viruses which destroys them through the process known as cell lysing. Human, animal and plant cells are “designed” to be in the sunlight and have cell walls that are less porous and are not harmed by atmospheric hydroxyl radicals.
WHAT MAKES PURE-LIGHT BULBS UNIQUE?
Though the properties of TiO2 are well documented, there have been problems in the past with applications:
* The first problem is that the photocatalytic process of TiO2 works well with sunlight or high power UV lights but not with ordinary light. PURE-LIGHT overcomes this by using a newly developed proprietary enhanced TiO2 formulation (Z-TiO2) that works extremely well with ordinary light. PURE-LIGHT TECHNOLOGIES has the exclusive rights to use this new formulation on light bulbs.
* The second problem is getting the TiO2 to "stick" to a surface longer than a few weeks or months. That is why other companies have tried to do it, but it has not worked very well for them. PURE-LIGHT has developed a new patent pending process that can "seal" the TiO2 to the surface of a light for up to 10 years. Since PURE-LIGHT developed it, no one else has it.
PURE-LIGHT TECHNOLOGIES LAB STUDIES
Below are a number of studies that delve into the properties and uses of titanium dioxide nanoparticles.
Compared to Chlorine disinfection, Ozonation, irradiation using germicidal lamps which all have problems, the TiO2 photocatalytic process is Nontoxic, chemically stable, safe, nonhaxardous and ecofriendly.
Applications of Photocatalytic Disinfection - Hindawi
Applications of photocatalytic processes are widely recognized as viable solutions to environmental problems [1–3]. Disinfection of bacteria is of particular importance, because traditional methods such as chlorination are chemical intensive and have many associated disadvantages. For example, in water treatment applications, chlorine used for disinfection can react with organic material to generate chloro-organic compounds that are highly carcinogenic [4, 5]. Furthermore, some pathogens such as viruses, certain bacteria such as Legionella, and protozoans such as Cryptosporidium and Giardia lamblia cysts have been known to be resistant to chlorine disinfection [6, 7]. Other treatment alternatives such as ozonation and irradiation using germicidal lamps (254 nm) have their own problems and limitations, such as the lack of residual effect  and generation of small colony variants  for the latter and production of toxic disinfection byproducts for the former .
In comparison, the semiconductor commonly used in photocatalytic processes is nontoxic, chemically stable, available at a reasonable cost, and capable of repeated use without substantial loss of catalytic ability . Heterogeneous photocatalysis using titanium dioxide is a safe, nonhazardous, and ecofriendly process which does not produce any harmful byproducts. Extensive research in this field has been done in the area of photocatalytic removal of organic, inorganic, and microbial pollutants [12, 13].
International Journal of Photoenergy Volume 2010 (2010), Article ID 764870, 11 pages
Due to the superior ability of photocatalysis to inactivate a wide range of harmful microorganisms, it is being examined as a viable alternative to traditional disinfection methods such as chlorination, which can produce harmful byproducts. Photocatalysis is a versatile and effective process that can be adapted for use in many applications for disinfection in both air and water matrices. Additionally, photocatalytic surfaces are being developed and tested for use in the context of “self-disinfecting” materials. Studies on the photocatalytic technique for disinfection demonstrate this process to have potential for widespread applications in indoor air and environmental health, biological, and medical applications, laboratory and hospital applications, pharmaceutical and food industry, plant protection applications, wastewater and effluents treatment, and drinking water disinfection. Studies on photocatalytic disinfection using a variety of techniques and test organisms are reviewed, with an emphasis on the end-use application of developed technologies and methods.
Interpretive Summary: Salmonella and Listeria are commonly detected in both raw and ready-to-eat meat products, and are responsible for many outbreaks of foodborne diseases in the USA. Nano-TiO2 has been demonstrate to be very effective to inhibit microbial growth under UV light, and is considered as a novel material that can be used for eliminating microbial pathogens from food. The objective of this study was to investigate the antimicrobial effects of nano-TiO2 particles on bacterial pathogens, Salmonella typhimurium and Listeria Monocytogenes, which are commonly found on raw and/or cooked poultry meat products. Our results show that nano-TiO2 effectively reduced the populations of either of the pathogens under UV light. Its effectiveness could be affected by nano-TiO2 concentrations and the initial microbial populations. L. monocytogenes was more resistant to nano-TiO2 treatment than Salmonella. Electronic microscopic images showed that under UV light, nano-TiO2 resulted in damage of bacterial cell walls, release of cell components, and subsequently the cell death. These results demonstrate that we can use nano-TiO2 to treat food products and reduce the risk of foodborne diseases by reducing pathogen populations and/or inhibiting pathogen growth.
Studies of photokilling of bacteria using titanium dioxide nanoparticles
Metal pins used to apply skeletal traction or external fixation devices protruding through skin are susceptible to the increased incidence of pin site infection. In this work, we tried to establish the photokilling effects of titanium dioxide (TiO2) nanoparticles on an orthopedic implant with an in vitro study. In these photocatalytic experiments, aqueous TiO2 was added to the tested microorganism. The time effect of TiO2 photoactivation was evaluated, and the loss of viability of five different bacteria suspensions (Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Enterococcus hirae, and Bacteroides fragilis) was examined by the viable count procedure. The bactericidal effect of TiO2 nanoparticle-coated metal plates was also tested. The ultraviolet (UV) dosage used in this experiment did not affect the viability of bacteria, and all bacteria survived well in the absence of TiO2 nanoparticles. The survival curve of microorganisms in the presence of TiO2 nanoparticles showed that nearly complete killing was achieved after 50 min of UV illumination. The formation of bacterial colonies above the TiO2 nanoparticle-coated metal plates also decreased significantly. In this study, we clearly demonstrated the bactericidal effects of titanium dioxide nanoparticles. In the presence of UV light, the titanium dioxide nanoparticles can be applicable to medical facilities where the potential for infection should be controlled.
Technology For Growing Plants In Space Leads To Device That Destroys Pathogens, Like Anthrax
Building miniature greenhouses for experiments on the International Space Station has led to the invention of a device that annihilates anthrax -- a bacteria that can be deadly when inhaled.
"Space-based greenhouses may seem to have little to do with the war against terrorism," said Mark Nall, director of the Space Product Development Program at NASA's Marshall Space Flight Center in Huntsville, Ala. "Yet this invention shows how commercial space research can benefit people on Earth in unexpected ways."
The anthrax-killing air scrubber, AiroCide Ti02, is a tabletop-size metal box that bolts to office ceilings or walls. Its fans draw in airborne spores and airflow forces them through a maze of tubes. Inside, hydroxyl radicals (OH-) attack and kill pathogens. Most remaining spores are destroyed by high-energy ultraviolet photons.
"Spores that pass through the box aren't filtered -- they're fried," said John Hayman, president of KES Science & Technology Inc., the Kennesaw, Ga.-company that manufactures AiroCide Ti02. "That's appealing because you don't have to change an anthrax-laden air filter."
The technology to build the anthrax killer emerged from another product, Bio-KES, which is used by grocers and florists to remove ethylene and thus extend the life of vegetables, fruits and flowers. Ethylene (C2H4) is a gas released by the leaves of growing plants -- but too much of it can build up in an enclosed plant growth chamber or produce storage facility.
Too much ethylene causes plants to mature too quickly, fruit to ripen prematurely, and it even accelerates decay. This hinders researchers' efforts to harvest healthy plants grown in space and would also be undesirable when space travelers build larger space-based greenhouses for growing fresh food.
The research that led to the invention of Bio-KES started with a crucial discovery made in the early 90's by scientists at the Wisconsin Center for Space Automation and Robotics - a NASA Commercial Space Center at the University of Wisconsin-Madison. These scientists collaborated on the discovery with Dr. Marc Anderson, a professor and chemist who also works at the university.
The research team found that ultra-thin layers of titanium dioxide (TiO2) exposed to ultraviolet light converted ethylene into carbon dioxide (CO2) and water (H2O) -- substances that are good for plants. Subsequently, they developed a coating technology that applies TiO2 layers to the surfaces of many materials.
UCL scientists develop novel approaches for killing MRSA and E.coli
Dr Sean Nair, Michael Wilson
New research from the UCL Eastman Dental Institute and UCL Chemistry, presented at the spring conference of the Society for General Microbiology (SGM), has provided a potential drug for MRSA treatment and a new antibacterial coating using Titanium Dioxide which will help fight hospital-acquired infections.
Research from the UCL Eastman Dental Institute has resulted in the development of a light-activated drug that could be used in the treatment of infections caused by the hospital bug MRSA. Researchers attached an antimicrobial drug, which is activated by light, to a peptide (a protein fragment) that binds onto a molecule on the surface of the superbug bacteria. Such light-activated antimicrobial agents produce free radicals and an unstable form of oxygen when they are exposed to light at the right wavelength. The release of these free radicals damages and ultimately kills bacteria. 99.97% of 10 million MRSA cells were killed using this new combination, which was 1,000 times more effective at killing MRSA compared to the commercially available SnCe6 when the same quantity is used.
Ivan Parkin, Dr Charles Dunnill, Michael Wilson, Dr Jonathan Pratten, and Zoie Aiken from the UCL Eastman Dental Institute have developed a hard coating with antibacterial properties that has been shown to kill 99.9% of 10 million Escherichia coli (E.coli) bacteria when a white hospital light was shone on its surface. The veneer-like surface is made of titanium dioxide with added nitrogen. When it is activated by white light, similar to those used in hospital wards and operating theatres, it produces a decrease in the number of bacteria surviving on the test surface. The hospital environment acts as a reservoir for the microbes responsible for healthcare-associated infections (HCAI) and new ways of preventing the spread of these pathogens to patients are needed. Antibacterial coatings could be applied to frequently touched hospital surfaces to kill any bacteria present and help reduce the number of HCAI. Titanium dioxide based coatings are known to kill bacteria after activation with UV light. The addition of nitrogen to these coatings enables photons (the basic unit of light) available in visible light to be utilised to activate the surface and kill bacteria.
PC Maness, S Smolinski, DM Blake… - Applied and …, 1999 - Am Soc Microbiol
When titanium dioxide (TiO2) is irradiated with near-UV light, this semiconductor exhibits strong bactericidal activity. In this paper, we present the first evidence that the lipid peroxidation reaction is the underlying mechanism of death of Escherichia coli K-12 cells that are irradiated in the presence of the TiO2 photocatalyst. Using production of malondialdehyde (MDA) as an index to assess cell membrane damage by lipid peroxidation, we observed that there was an exponential increase in the production of MDA, whose concentration reached 1.1 to 2.4 nmol z mg (dry weight) of cells21 after 30 min of illumination, and that the kinetics of this process paralleled cell death. Under these conditions, concomitant losses of 77 to 93% of the cell respiratory activity were also detected, as measured by both oxygen uptake and reduction of 2,3,5-triphenyltetrazolium chloride from succinate as the electron donor. The occurrence of lipid peroxidation and the simultaneous losses of both membrane-dependent respiratory activity and cell viability depended strictly on the presence of both light and TiO2. We concluded that TiO2 photocatalysis promoted peroxidation of the polyunsaturated phospholipid component of the lipid membrane initially and induced major disorder in the E. coli cell membrane. Subsequently, essential functions that rely on intact cell membrane architecture, such as respiratory activity, were lost, and cell death was inevitable.
Z Huang, PC Maness, DM Blake, EJ Wolfrum… - … of Photochemistry and …, 2000 - Elsevier
When exposed to near-UV light, titanium dioxide (TiO2) exhibits a strong bactericidal activity. However, the killing mechanism(s) underlying the TiO2 photocatalytic reaction is not yet well understood. The aim of the present study is to investigate the cellular damage sites and their contribution to cell death. A sensitive approach using o-nitrophenol β-d–galactopyranosideside (ONPG) as the probe and Escherichia coli as model cells has been developed. This approach is used to illustrate damages to both the cell envelope and intracellular components caused by TiO2 photocatalytic reaction. Treatment of E. coli with TiO2 and near-UV light resulted in an immediate increase in permeability to small molecules such as ONPG, and the leakage of large molecules such as β-d–galactosidase after 20 min. Kinetic data showed that cell wall damage took place in less than 20 min, followed by a progressive damage of cytoplasmic membrane and intracellular components. The results from the ONPG assay correlated well with the loss of cell viability. Cell wall damage followed by cytoplasmic membrane damage leading to a direct intracellular attack has therefore been proposed as the sequence of events when microorganisms undergo TiO2photocatalytic attack. It has been found that smaller TiO2 particles cause quicker intracellular damage. Evidence has been obtained that indicated that the TiO2photocatalytic reaction results in continued bactericidal activity after the UV illumination terminates.
Titanium Dioxide: Toxic or Safe?
Titanium dioxide is the subject of new controversy, yet it is a substance as old as the earth itself. It is one of the top fifty chemicals produced worldwide. It is a white, opaque and naturally- occurring mineral found in two main forms: rutile and anatase. Both forms contain pure titanium dioxide that is bound to impurities. Titanium dioxide is chemically processed to remove these impurities, leaving the pure, white pigment available for use. Titanium dioxide has a variety of uses, as it is odorless and absorbent. This mineral can be found in many products, ranging from paint to food to cosmetics. In cosmetics, it serves several purposes. It is a white pigment, an opacifier and a sunscreen. Concern has arisen from studies that have pointed to titanium dioxide as a carcinogen and photocatalyst, thus creating fear in consumers. But are these claims true? What does the research on these allegations bear out? Would we as consumers benefit from avoiding this mineral to preserve our long-term health?
A carcinogen is a substance that causes a cellular malfunction, causing the cell to become cancerous and thus potentially lethal to the surrounding tissue and ultimately the body as these rapidly growing mutated cells take over. With the surge in cancer rates among all segments of the population, many people are attempting to reduce or eliminate their exposure to carcinogens. Titanium dioxide is regarded as an inert, non-toxic substance according to its Material Safety Data Sheet (MSDS).
Use of TiO2 photocatalytic process for removal of airborne organic pollutants, VOCs appear to be superior to traditional technologies.
Applications of Photocatalytic Disinfection - Hindawi, Joanne Gamage and Zisheng Zhang
Department of Chemical and Biological Engineering, University of Ottawa, 161 Louis Pasteur, Ottawa, ON, K1N6N5, Canada
The photocatalytic process is well recognized for the removal of organic pollutants in the gaseous phase such as volatile organic compounds (VOCs), having great potential applications to contaminant control in indoor environments such as residences, office buildings, factories, aircrafts, and spacecrafts [40, 41].
To increase the scope of the photocatalytic process in application to indoor air, the disinfection capabilities of this technique are under investigation . Disinfection is of importance in indoor air applications because of the risk of exposure to harmful airborne contaminants. Bioaerosols are a major contributor to indoor air pollution, and more than 60 bacteria, viruses, and fungi are documented as infectious airborne pathogens. Diseases transmitted via bioaerosols include tuberculosis, Legionaries, influenza, colds, mumps, measles, rubella, small pox, aspergillosis, pneumonia, meningitis, diphtheria, and scarlet fever . Traditional technologies to clean indoor air include the use of activated charcoal filters, HEPA filters, ozonation, air ionization, and bioguard filters. None of these technologies is completely effective .
In the pioneering work by Goswami et al. [43, 44] investigating the disinfection of indoor air by photocatalysis, a recirculating duct facility was developed to inactivate biological contaminants in air with photocatalytic techniques. Experiments using Serratia Marcescens in air achieved a 100% destruction of microorganisms in a recirculating loop in 600 minutes . This time was reduced to less than 3 minutes in later experiments .
Photocatalytic oxidation can also inactivate infectious microorganisms which can be airborne bioterrorism weapons, such as Bacillus anthracis (Anthrax) [46–48]. A photocatalytic system was investigated by Knight in 2003 to reduce the spread of severe acute respiratory syndrome (SARS) on flights , following the outbreak of the disease. Similarly, in 2007 the avian influenza virus A/H5N2 was shown to be inactivated from the gaseous phase using a photocatalytic prototype system .